Welcome to the Down syndrome metabolic health study page!

The Down syndrome Metabolic Health Study is a multi-site research study taking place at both Children's Hospital of Philadelphia (CHOP) in Philadelphia, PA and Children's National Medical Center (CNMC) in Washington, DC. The study is trying to learn more about how body composition relates to the risks of developing heart disease and type 2 diabetes in children and adolescents with Down syndrome. The information obtained from this study may help us better understand how to identify risk factors in kids with Down syndrome, so doctors can work to prevent metabolic health problems.

Please browse through our website, learn more about the study and these health risks in individuals with Down syndrome, and find out if you're eligible or how you can help! Happy exploring!

Young Woman with Down Syndrome

Our study has grown and gained a second home at Children's National Medical Center (CNMC) in Washington, DC!

Children's National Health System logo

We are now recruiting patients to participate at both CHOP and CNMC. You can learn more about our study's growth and our new study location throughout our site!

Visit our "Controls Page" to learn more about the important role of control patients, and the reason we may need YOU to help with our study!

Meet the study team!

This study is made up of a great team of people, dedicated to learning more about the health of children and adolescents with Down syndrome. Get to know more about them and their work here.


Whether you are a current, new, or maybe future participant, you can find all of the forms and documents you need to learn more about our study on our Study Resources page.

Study Progress

Want to know how many people have participated in our study so far? Check out our Recruitment Progress page to see how far we've come!